Histopathological Changes in Multiple Fetal Tissues Exposed In-Utero to Zidovudine
نویسندگان
چکیده
منابع مشابه
Neurobehavioral changes in mice exposed to fast neutrons in utero.
Epidemiological studies have revealed that radiation causes brain development abnormalities in atomic bomb survivors exposed in utero. Rat and mouse studies have also shown that prenatal exposure to low-linear energy transfer radiation induces developmental brain anomalies. Because the effects of prenatal irradiation on adult behavior patterns remain largely unknown, the present study investiga...
متن کاملComparing genotoxic signatures in cord blood cells from neonates exposed in utero to zidovudine or tenofovir
OBJECTIVES Zidovudine and tenofovir are the two main nucleos(t)ide analogs used to prevent mother-to-child transmission of HIV. In vitro, both drugs bind to and integrate into human DNA and inhibit telomerase. The objective of the present study was to assess the genotoxic effects of either zidovudine or tenofovir-based combination therapies on cord blood cells in newborns exposed in utero. DE...
متن کاملHistopathological changes of gill, liver and kidney in Caspian kutum exposed to Linear Alkylbenzene Sulfonate
The histopathological effects of Linear Alkylbenzene Sulfonate on the gill, liver and kidney tissues of the Caspian kutum, Rutilus frisii kutum were studied. The fish were exposed to three sublethal concentrations of anionic detergent, Linear Alkylbenzene Sulfonate (LAS) for short term intervals (192 h). Gill, liver and kidney samples were collected after 192 h of exposure to LAS and lesions we...
متن کاملHistopathological changes of gill, liver and kidney in Caspian kutum exposed to Linear Alkylbenzene Sulfonate
The histopathological effects of Linear Alkylbenzene Sulfonate on the gill, liver and kidney tissues of the Caspian kutum, Rutilus frisii kutum were studied. The fish were exposed to three sublethal concentrations of anionic detergent, Linear Alkylbenzene Sulfonate (LAS) for short term intervals (192 h). Gill, liver and kidney samples were collected after 192 h of exposure to LAS and lesions we...
متن کاملHistopathological changes in liver of Heteropneustes fossilis exposed to cypermethrin.
Cypermethrin was administered to Heteropneustes fossilis in chronic concentration to determine lesion of liver as indicators of tissue damage. The cypermethrin dose used was 1/4 of 96 hr LC50. Histopathological changes in liver ranged from vacuolization, necrosis, fibrosis of perivascular region and disposition of yellow brown grains at different time of exposure viz; 20th, 30th, 40th and 60th ...
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ژورنال
عنوان ژورنال: Journal of AIDS & Clinical Research
سال: 2014
ISSN: 2155-6113
DOI: 10.4172/2155-6113.1000373